5-Hydroxytryptamine1D Receptor
《英文msh詞典》5-Hydroxytryptamine1D Receptor
[入口詞] 5-Hydroxytryptamine1D Receptor
[主題詞] Receptor,Serotonin,5-HT1D
[英文釋義] A serotonin receptor subtype that is localized to the CAUDATE NUCLEUS; PUTAMEN; the NUCLEUS ACCUMBENS; the HIPPOCAMPUS,and the RAPHE NUCLEI. It plays a role as a terminal autoreceptor that regulates the rate of SEROTONIN release from nerve endings. This serotonin receptor subtype is closely related to and has similar drug binding properties as the 5-HT1B RECEPTOR,but is expressed at low levels. It is particularly sensitive to the agonist SUMATRIPTAN and may be involved in mediating the drug's antimigrane effect.